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Clinical symptoms disappeared or improved markedly and rapidly in the vast majority of patients

Discovery, structureactivity relationships, and in vivo activity of dihydropyridone agonists of the bile acid receptor TGR5

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can be used, but they should NOT be given if there is possibility patient is pregnant Oral contraceptives - very small study that showed some improvement Metformin - can help promote weight loss, which can help HS For acute symptomatic lesions - warm compress May want to refer out for this: possibility of intralesional corticosteroid injections Unroofing the area over the nodule I&D - not advised for routine treatment