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Mechanisms of protection against free-radical-mediated liver cell injury, in: Free radicals in liver injury , Slater, T

By influencing S-adenosylmethionine (SAM) levels, it also plays a role in epigenetic regulation and longevity-related gene expression, linking energy metabolism with cellular lifespan

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While most men tolerate B12 well, those with Lebers disease (a rare genetic eye disorder) should avoid injections, as high doses of B12 may worsen symptoms

This apparent paradox is explained by the peptides ability to trigger cascading gene expression changes that continue operating long after the peptide itself has been cleared