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Distinctive features of LCHAD deficiency are progressive pigmentary retinopathy and peripheral neuropathy

( a-b ) Representative immunohistochemistry images ( a ) and quantification ( b ) of OLFM4 + cells in WT and PPAR-3KO mice on CD or KD

Its primary role is to transport stored fat into the mitochondria the power plants of your cells where it can be burned for energy

HikitaTKodamaHNakamotoNKagaFAmakataKOgitaKet al

Therefore, it is necessary to understand how a variety of intrinsic and extrinsic factors are integrated to create the metabolic flexibility and to reduce the metabolic dependencies dictated by oncogenic signaling