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Notably, these macrocyclic peptides exhibit noncompetitive behavior with either SAM or NAM, suggesting that they may function as allosteric inhibitors targeting NNMT (Van Haren et al., 2021)

Exp Ther Med

It has therapeutic properties, including a neuroprotective effect (Wang et al., 2015

Cortisol regulation: The stress hormone cortisol, when chronically elevated, impairs memory consolidation, disrupts sleep, and erodes emotional resilience