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Only once the vial has reached ambient temperature should the seal be broken

10.1016/S0140-6736(20)31824-9 12

Some compounders use shorter windows depending on testing

See also: Poisoning acute guidelines for initial management Resuscitation Relevant sections in this guideline For 24-hour advice, contact the Poisons Information Centre 13 11 26 Single immediate release paracetamol ingestion Modified release paracetamol ingestion Repeated supratherapeutic paracetamol ingestion Acetylcysteine infusion instructions Intravenous paracetamol medication errors are not covered in these guidelines and must be discussed with Poisons Information Centre or a clinical toxicologist Key points Suspect paracetamol poisoning in all deliberate adolescent self-poisonings and consider other co-ingestants Time to acetylcysteine is crucial in protecting the liver from significant toxicity

Depletion of omega-3 fatty acid levels in red blood cell membranes of depressive patients Biol Psychiatry 1998