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Significantly higher levels of activated NK cells were observed in the TME of tumors with high PKMYT1 expression over tumors with low PKMYT1 expression [135]

doi: 10.1111/j.1753-4887.2004.tb00030.x 60 ParraMStahlSHellmannH

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Substantial evidence has been provided that IIS is an evolutionarily conserved pathway that regulates lifespan across many species like flies, worms, and mice [36]