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It is involved in cell adhesion, proliferation, migration, and angiogenesis ( in-vitro matured mouse cumulus-oocyte complexes mice injected with HCG resulted in significantly down-regulated transcription and translation of the versican gene in follicles ( in vitro mouse oocyte maturation, cumulus-specific genes like PTGS2, TNFAIP6, and HAS2 become more significant ( The variance in all these genes expression is possibly due to different materials and methods used in the studies

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These gaps highlight the need for future research to move beyond single-cell type and descriptive mechanisms toward systematic dissection of intercellular crosstalk, renal parenchymal cell contributions, and clinical validation

Round JL, OConnell RM, Mazmanian SK

The total higher alcohol concentration ranged from 304 mg/L (control) to 328 mg/L (BF_V3), which falls within the typical range reported in the literature (Francis & Newton, 2005