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Published 2017 Jul 27

doi: 10.1016/j.schres.2020.07.020, 77

MCC950 lowers autophagic markers via an mTOR-linked route, and rapamycin rescues both autophagy and phenotype, indicating feedback from NLRP3 into autophagy set-points

Cagrilintide acts as an amylin receptor agonist , binding to amylin receptors which are complexes of the calcitonin receptor with receptor activity-modifying proteins (RAMPs)