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The senescence problem To appreciate the significance of FOXO4-DRI, it helps to understand cellular senescence and why it matters in ageing and disease

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Vervloet MG, Massy ZA, Brandenburg VM, Mazzaferro S, Cozzolino M, Urea-Torres P, Bover J, Goldsmith D

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Given the high dependence of follicular cells and oocytes on mitochondrial integrity and bioenergetic capacity, it is plausible to hypothesize that lipid droplet-mediated mitophagy could contribute to follicular development and oocyte maturation

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Kallistatin: a novel human tissue kallikrein inhibitor

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