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23- Ronnenberg AG, Venners SA, Xu X, Chen C, Wang L, Guang W, Huang A, Wang X

In senescent cells, NF-B is often constitutively activated, driving chronic inflammation.131 Senomorphic agents can inhibit this pathway, reducing the secretion of inflammatory cytokines and alleviating the deleterious effects of chronic inflammation.132 JAK/STAT Pathway: The Janus kinase (JAK) signal transducer and activator of transcription (STAT) pathway is involved in the inflammatory signaling of senescent cells

Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents