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When NGF levels drop due to aging or chronic stress, we experience slower learning, poor memory recall, and a general sense of mental rigidity

In the case of iron metabolic disorder, the low expression of FTH1 and the overexpression of TFR1 often lead to the excessive accumulation of Fe 2+ ions, which induce the production and accumulation of a large amount of ROS through Fenton reaction and eventually promote cell ferroptosis ( Lipid Peroxidation Lipid peroxidation plays a driving role in the occurrence of ferroptosis, which can be completed by non-enzymatic or enzymatic reaction

Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C et al (2015) Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

Nematode-derived immunomodulatory molecules include mimics of host immune mediators as well as novel molecules that are unique to parasites themselves

What is truly promising is that there appears to be little to no toxicity in non-neoplastic cells