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The glycine modulatory site of the NMDAR is currently a favored therapeutic target, with several modulatory agents currently undergoing clinical development

Menoufia Med J

Organisms Homo sapiens Communities Inherited Metabolic Disorders (IMD) Pathways ONTOX Rare Diseases Annotations Disease Ontology autosomal recessive disease metabolic acidosis gamma-glutamyl transpeptidase deficiency hemolytic anemia Pathway Ontology glutathione metabolic pathway glutathione biosynthetic pathway disease pathway amino acid metabolic pathway glutathionuria disease pathway References Glutathionuria: inborn error of metabolism due to tissue deficiency of gamma-glutamyl transpeptidase

Mutations of multiple genes cause deregulation of NF-B in diffuse large b-cell lymphoma

Correlation between induction of T-cell cytotoxicity by anti-CD3 bispecific T-cell engagers and increased expression level of antigens on target cells has previously been shown and associated with epitope location and the size of the extracellular domain of the targeted tumour-associated antigen 34,36