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doi: 10.1002/hep.30249 173 PonzianiFRBhooriSCastelliCPutignaniLRivoltiniLDel ChiericoFet al

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The oxidative stress caused by dying rods then causes degeneration of the cones, which at only 2% of the photoreceptors in the mouse retina, become overwhelmed by the oxidative damage [44, 45]

Genetic diagnosis First-line genetic testing to confirm a diagnosis of SPIGFD typically involves sequencing of the GHR gene or other genes involved in the GH-IGF axis (Table 1) [37]

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