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10.3233/JAD-142334 59 XuP

If not promptly eliminated, they can cause damage to the body, including lipid peroxidation, protein carbonylation, and DNA damage, potentially leading to various diseases

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Notably, the inactivation of this enzyme is responsible for cerebrotendinous xanthomatosis (OMIM 213700), a rare autosomal recessive lipid storage disease associated with central demyelination, ataxia and spastic paraplegia

Six studies over two decades consistently show protective effects against alcohol damage to the stomach, liver, brain, kidneys, and lungs