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Wu, X., Liu, J., Li, D

Depurinating estrogen-DNA adducts, generators of cancer initiation: Their minimization leads to cancer prevention

Providing ketone monoesters in the fasted state maximizes the state of ketosis, reaching peak circulating HB concentrations above 2 mM (19, 39, 40, 49), which are blunted in the fed state (19)

The most significant marker, considered a gold standard, was F2-isoprostane and this was significantly more reduced by oral Acetylglutathione than with the IV glutathione.[11],[12] Oral S-Acetyl Glutathione, dosed 200mg daily for 7 days, AM IV 1400mg, single dose Serum and urine tested after 1 week of administration N=6, (4 female, 2 male, average age 45) Markers chosen are measures of Antioxidants F2-Isoprostane is the Gold Standard of oxidative stress markers Conclusion: Oral S-A GSH compares favourably to a one-time, equivalent dose of IV administered Glutathione GSH : Blood levels are lower in the A-GSH group as compared to the IV group because the A-GSH is being taken up by the cell.[13] This is substantiated by the following markers: F2-Iso : (F2- isoprostane ) measurement of redox status and oxidative stress

10.1038/nn1797 56 HuangQ.Figueiredo-PereiraM