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J Toxicol Clin Toxicol 40(6):789801 ten Berg K, van Oppen ACC, Nikkels PGJ, Gittenberger-de Groot AC, Vander Voet GB, Brilstra EH, Lindhout D (2005) Complex cardiac defect with hypoplastic right ventricle in a fetus with valproate exposure

found that (110), AD can reduce the production of anti-CII, TNF, IL-1 and IL-6 in the serum of CIA mice, and can also decrease the phosphorylation of p38 MAPK and ERK1/2 in RASFs induced by TNF in a dose-dependent manner