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Treatments with either Gepon, obtained in pharmaceutical-grade purity, or recombinant TGF-1 were performed in low-serum conditions

Archived from the original on September 3, 2014

This mismatch constitutively activates IRP1, which orchestrates a tripartite response: upregulation of TfR1, translational repression of ferritin, and activation of NCOA4-mediated ferritinophagy