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Additional work has to be done to improve treatments that deal with the colonization and recolonization of the periodontal pocket by microbes to reduce antibiotic use and the cumulative negative effects of recurrent therapy [94]

doi: 10.1016/S0968-0896(00)82013-1 48 FerriA

Postmenopausal osteoporosis (type I): After menopause, women experience a sudden drop in estrogen levels, a significant increase in osteoclast activity, accelerated bone resorption, insufficient osteoblast activity, and rapid loss of bone mass (30% -50% loss after 5-10 years of menopause), mainly in the lumbar spine and hip

Reseal the pouch tightly after each use

doi: 10.1002/ijc.28114 308 LanZLiuW-JYinW-WYangS-RCuiHZouK-Let al