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In early-stage exhaustion, PD-1 + T cells demonstrated less reliance on oxidative phosphorylation (OXPHOS) and glycolysis

Figure 5 3.4.1 Macrophages In response to environmental stimuli, macrophages can polarize into different phenotypes, demonstrating their extraordinary adaptability

Figure 7 LA Supplementation Prevented FA-Induced xCT Reduction by Inhibiting p53 Activation P53 served as a major factor of cellular ferroptosis that respond to various injuries, and we further examined whether LA can protect from ferroptosis that was associated with p53 activation in tubular epithelial cells

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In agreement with the previous studies, all three H1.4 variants displayed pronounced protection at the nucleosomal dyads, consistent with an on-dyad binding mode of their GH1 domains, as observed in the cryo-EM structure of an H1.4-containing chromatosome 10