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Ziegler D, Low PA, Freeman R, Tritschler H, Vinik AI (2016) Predictors of improvement and progression of diabetic polyneuropathy following treatment with -lipoic acid for 4 years in the NATHAN 1 trial

also known as mechanotarget of rapamycin complex 2) is a serine/threonine kinase made up of several protein components, including mTOR, and has the ability to phosphorylate a number of downstream targets to integrate upstream growth factor stimulation with cellular processes (such as cell survival) (104)