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Additionally, it involves various hallmarks such as insulin resistance, adipose tissue dysfunction, chronic inflammation, gut microbiota, lipid dysregulation, and genetic predispositions ( Figure 1 )

This phenomenon could be attributed to the fact that ethanol exposure accelerated the pathological process of AD, which in turn damaged the antioxidant capacity in APP/PS1 mice

Brain 144 , 12961311 (2021)

By using cells and supernatant to measure each with different indicators, a more detailed analysis of cell death can be achieved

The levels of 5-MeTHF and THF were unchanged by dietary MET in Ames dwarf mice but were higher in wild-type mice on the 0.16% level of MET (Figure 2)