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Occupational risk factors for the development of systemic lupus erythematosus

First, much of the mechanistic evidence derives from animal or cell-based studies, whereas human data are comparatively scarce and often limited to small cohorts or end-stage HF biopsies (Lopaschuk et al., 2010)

Complementary findings demonstrated that systemic immune activation via LPS in mice produced sustained reductions in novel object exploration for up to 24 h (Haba et al., 2012)

Worth knowing: These effects are largely based on anecdotal reports