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In this study, we recruited 17 OC patients, 16 benign ovarian tumor (BOT) patients, and 14 control patients to collect biological samples including ovary plasma, urine, and hair from the same patient

Monami M, Candido R, Pintaudi B, Targher G, Mannucci E

The findings of a clinical trial demonstrated that silymarin administration diminished the incidence of anti-tuberculosis drugs induced-liver injury which can be attributed to a lower reduction in the level of superoxide dismutase compared to the control group [146]

However more researches suggested that it was oxidized LDL instead of heme itself ascribed as the cause for the induction of heme oxygenase-1 and ferritin, since when catalyzing the oxidation of LDL, heme itself underwent degradation (Nath et al., 1995

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