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This is due to various factors, including poor diets, malabsorption of vitamins, and certain medical conditions and medications which can contribute to lower levels of vitamin B12 in the body

"If the FDA flipped a switch tomorrow, you're going to have prescribers and patients dashing to their compounding pharmacy only to be frustrated," he says

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CCL2 , IL10 , IL1RA , and IL6 were not differentially expressed when impaired and non-impaired individuals were compared, and these genes did not respond to incubation with B12 (Additional file 4)