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Brain doi: 10.1093/brain/awae270

The body obtains vitamin D either from fungi-based diet (vitamin D2) or animal source (vitamin D3), by endogen synthesis in sun-exposed skin (vitamin D3) or by supplements

Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis

Reduces pigmentation and dark spots Glutathione injection for skin whitening also helps break down pigmentation caused by the sun or acne scars, giving the skin a clearer appearance

Overexpression of IRP2 or MPP + treatment significantly enhances the binding of IRP2 to p53 in PC-12 cells, upregulates p53 levels, downregulates SLC7A11 expression, and increases arachidonate 12-Lipoxygenase (ALOX12) expression, thereby promoting ferroptosis and amino acid antioxidant system disruptions, elevating MDA levels, and inducing PC-12 cell damage