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This binding may signal and trigger numerous pathways in organisms related to protein synthesis and adipose tissue reduction

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doi: 10.3389/fchem.2018.00204 29 HuanY.KongQ.MouH.YiH

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Unlike other organelles such as mitochondria, where an abundance of reduced glutathione (GSH) preserves a reductive environment, the ER requires an oxidizing milieu to facilitate the formation of disulfide bonds critical for protein structural integrity