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doi: 10.3389/fmicb.2018.02050 Received 26 January 2018 Accepted 13 August 2018 Published 31 August 2018 Volume 9 - 2018 Edited by Rosalba Lanciotti, Universit degli Studi di Bologna, Italy Reviewed by Panagiotis Skandamis, Agricultural University of Athens, Greece

This reaction is catalyzed by the enzyme transketolase and involves the transfer of the two carbon groups on xylulose 5-phosphate onto the erythrose 4-phosphate

Impaired function of the MPC is frequently observed in specific CRC subtypes, driving a metabolic shift toward glycolysis, enhancing stemness, and conferring resistance to OXPHOS inhibitors [52, 53]

Furthermore, it showed that ED-71 can repair LPS-induced pyroptosis via the NLRP3 inflammasome in HGFs