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Initial low-dose gentamicin for Staphylococcus aureus bacteremia and endocarditis is nephrotoxic

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Meperidine (initial dose 2550 mg i.v.) has shorter half-life but puts patients are at higher risk of metabolite accumulation (neuromuscular side effects) when repeated doses accumulate

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[1] Shao L, Li QH, Tan Z

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