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Figure 5C summarizes the effect of increasing concentrations of urea on the CD ellipticity at 222 nm and the tryptophan emission maxima of Pf GST tetramers and dimers

Additionally, depletion of the calmodulin regulatory factor 1 (RCAN1) aggravates podocyte injury, impairs the glomerular filtration barrier and increases proteinuria, suggesting that RCAN1 is a protective factor for podocytes (127)