glutathione dehydrogenase ascorbate activity (Ascorbate) - an overview 4 Interaction between ascorbic acid

Sabeh, F., Fox, D

[34] Data showing that cysteine, N-acetylcysteine (NAC), reduced glutathione, and ascorbic acid all suppress NF-kB activity and HIV activation in cell lines [33] has resulted in the production of drugs like L-2-oxothiazolidine-4-carboxylic acid (OTC) or "Procysteine." While OTC has been shown to increase lymphocyte glutathione levels in healthy subjects, it is not itself an antioxidant and has not been shown to be as effective as N-acetylcysteine

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doi: 10.3389/fphar.2020.01021 162 JiangTGhoshRCharcossetC

CV-F and CG-L were fellows in the Programa de Doctorado en Ciencias Biomdicas and at the UNAM and were supported by the CONACYT fellowship Nos