Clinically observed benefits: What the research actually shows nothing added, nothing inflated
Key residues 38 YGSL 41 , D 68 , R 72 , E 115 and Y 143 are responsible for high affinity substrate binding via salt bridge interaction with the glutamate (E 115 ), hydrogen bonding as well as a cation -interaction involving Y 143
Mesquida M, Molins B, Llorenc V, et al
Arkivoc 307324 (2007)
The National Academy of Medicine recommends 120 g/day for men and 90 g/day for women, the World Health Organization (WHO) recommends 65 g/day for men and 55 g/day for women, and the European Communities recommend 75 g/day ( Vitamin K is essential for blood coagulation and acts as an essential coenzyme responsible for modifying glutamic acid residues in certain proteins to -carboxyglutamic acid residues ( Measuring Vitamin K levels in serum has been a challenge, thus relying on indirect markers like uncarboxylated osteocalcin ( The position of vitamin K in health and disease has been reported including roles in cardiovascular health, bone development, fractures, diabetes development, metastasis of multiple cancer cell lines, renal artery functions, immunosuppression, and protective effects on neurons ( 1.1 The mechanisms of vitamin K1 and K2 Vitamin K exists primarily in two forms relevant to human physiology: vitamin K1 (phylloquinone) and vitamin K2 (menaquinones)
