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doi: 10.1155/2020/1295381 186 AlvarezCLSchachterJde Sa PinheiroAASilva LdeSVerstraetenSVPersechiniPMet al

CAFs can also promote cancer growth and invasiveness, and both CAFS and ROS are linked through the increases in ROS-generated CAFs to which most cancers respond by increasing the expression of antioxidant genes 52,53,54 (Fig