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In the vascular wall, LDL can be modified (oxidized) by many cell types, including vascular smooth muscle cells, endothelial cells, and macrophages (776)

Secretion of cytokines, such as IL-22 and IL-17, could result in the hyperproliferative phenotype of keratinocytes and potentially synoviocytes, leading to a vicious cycle of cellular proliferation and inflammation in both the skin and joints

Wood SJ, Berger GE, Wellard RM, Proffitt T-M, McConchie M, Berk M, et al

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