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Optimal dosing varies based on individual factors including body weight, body composition goals, and metabolic responsiveness

In one retrospective analysis of anemia in pregnancy, researchers compared pregnant women who were taking high vitamin B12, high folic acid food with those who were taking standard prenatal food with low vitamin B12, low folic acid. The women in the vitamins-enriched prenatal balanced diet group had significantly higher hemoglobin levels at delivery than those in the standard prenatal food group

Patients were randomized (n=456) to receive pemetrexed 500 mg/m2 intravenously over 10 minutes followed 30 minutes later by cisplatin 75 mg/m2 intravenously over two hours on Day 1 of each 21-day cycle or to receive cisplatin 75 mg/m2 intravenously over 2 hours on Day 1 of each 21-day cycle

So, the route of administration matters

The Journal of international medical research