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Chinese herbal medicine for the treatment of depression: effects on the neuroendocrine-immune network

By introducing medical-grade ozone into the bloodstream or tissues, this therapy improves circulation, reduces inflammation, and strengthens the immune system

doi: 10.1001/jama.2010.1361 225 AshizawaKImaizumiMUsaTTominagaTSeraNHidaAet al

Oxidative stress is a leading cause of liver damage caused by various factors, such as drugs, viruses, ethanol, etc

In particular, they found that, in the absence of BMAL1, NF-B-driven transcription was upregulated by the core circadian protein CLOCK, whereas BMAL1 hindered the CLOCK-induced increase in the activation of NF-B-regulated genes 71