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These GSTs are further distinguished based on the presence of the ancestral cysteine (Cys-GSTs) present in TRX family proteins or on its substitution by a serine (Ser-GSTs)

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Acknowledgments A slightly expanded Chinese version of the abstract in this manuscript was submitted to the 20th Annual conference of Chinese Geriatrics Society in April 2023

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When mammalian cells experience irreversible disruptions in their internal or external milieu, they can initiate several signal transduction cascades that ultimately result in cell death (Kayagaki et al., 2024