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10.1083/jcb.200502019 255 RossitchE.Jr.AlexanderE.3rdBlackP

Uric acid in health and disease: from physiological functions to pathogenic mechanisms

Hence, whilst cysteine is one of the less common amino acids, it is often highly conserved within protein functional groups (Marino and Gladyshev, 2010)

Conclusion Collectively, we unveil GPR68 as a critical sensor of ischemic acidosis that orchestrates ferroptosis resistance via PI3K/Akt/Nrf2 signaling

The ESI-MS investigations were conducted in both negative and positive scanning mode enabling detection of both positively and negatively charged GSH and GSSG species, as well as (modified) iron(II) and iron(III) complexes