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Evidence of Heterogeneous and Variable Myelin Repair in MS Patients Observations of postmortem tissues from MS patients long ago raised the possibility of spontaneous myelin repair in humans (Prineas and Connell, 1979

Supplementation with 300-600 mg/day has been shown to increase intracellular glutathione levels by 30-70% in cell culture and animal studies, with more modest increases in human trials (Suh et al., Proc Natl Acad Sci, 2004) [25]

Experienced users consistently recommend starting at 2030mcg daily for 7 days to assess glucose tolerance before escalating dose

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This temporal regulation of autophagy genes promotes A degradation through the activation of astrocytic autophagy, whereas the pharmacological inhibition of autophagy exacerbates mitochondrial dysfunction and oxidative stress, ultimately leading to astrocyte death