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Moreover, two PLP-dependent enzymes are required to convert homocysteine to the amino acid cysteine in homocysteine transsulfuration pathway: cystathionine -synthase and cystathionine -lyase ( Figure 5 ) (34)

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Similarly, GPx8 suppression was recently shown to enhance ER stress in the liver (Lee et al., 2021)

Involvement of immune response in the pathogenesis of amyotrophic lateral sclerosis: A therapeutic opportunity