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Phase II - larger number of patients, designed to evaluate the safety and efficacy of the medicine and to determine if different dosages of the treatment have different effects

J Toxicol 2012:645460

In addition, the investigation and application of NZs in dentistry face a multitude of potential obstacles

Nitrite effectively impedes the activation of MMP2 via XO-mediated antioxidant mechanisms and reverses vascular structural alterations associated with hypertension (133)