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After 2 weeks, hepatocytes from each mouse were collected and de novo lipogenesis (DNL) was assessed as previously described 26

The EAR represents the level of vitamin B12 that is estimated to meet the B12 requirements of 50% of the healthy individuals in a particular sex and life-stage group

Yamamoto, Y., Abe, A

After sulfasalazine treatment, Gpx4 expression showed a slight increase toward baseline levels, whereas Acsl4 expression remained elevated

Pro-inflammatory cytokinessuch as IL-6, IL-1, TNF-, and IFN-can further upregulate hepcidin, disrupting the FPN/Hepcidin pathway and inhibiting iron export, thus affecting iron levels in the body