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As a proof of concept in treating oxidative stress-related diseases, the CuZnHis assemblies can promote the macrophage polarization from M1 to M2 phenotype and the expression of anti-inflammatory factors, and inhibit the periodontitis in male animal models (Fig

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Mice were euthanized 12 to 14 hours post-hCG injection, and cumulus cells were removed enzymatically using 0.3% hyaluronidase in M2 medium

Crystalloids are typically used to keep blood circulation going until blood products can be given to a patient with severe blood loss