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Notwithstanding their considerable potential, challenges such as achieving therapeutic concentrations in vivo and tissue-specific delivery impede clinical translation

In conclusion, the administration of oral tap water is associated with a sustained improvement in blood pressure when compared with patients who received intravenous saline solution

10.1093/jexbot/53.372.1321 25 Di MascioP.KaiserS.SiesH

Hydrogels designed for direct injection into the eye or those that gel in situ (crosslinking) or in response to temperature changes (thermogelling) also show a wide range of stiffness, though some direct injection and thermogelling/in situ crosslinking hydrogels have moduli closer to the human vitreous than others

Because GHK-Cu does not target the same biological mechanisms as finasteride or minoxidil, it may be used topically as a complementary step