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Note this index did not take into account overall individual variability in response output

The normality of the data distribution was assessed using the KolmogorovSmirnov test

"Long-term follow-up of antithyroid peroxidase antibodies in patients with chronic autoimmune thyroiditis (Hashimoto's thyroiditis) treated with levothyroxine"

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Data availability The bulk RNA-seq data generated in this study have been deposited in GEO Omnibus under the accession code GSE279885 ( The metabolomics data generated in this study have been included in the Source Data file