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Additionally, based on the number of amino acid residues in their structure, peptides can support many key processes in the body due to their antioxidant, antimicrobial, antibacterial, anti-inflammatory, antitumor, and immunoregulatory activities [11]

Sleep disturbance is also common in postmenopausal women 3 , with some studies showing that up to half of women experiencing a dramatic increase in sleep disturbance during the transition from perimenopause to menopause

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The neuroprotective effects of the ketogenic diet further extend to synaptic plasticity regulation: by increasing -hydroxybutyrate (BHB) levels, it directly activates the ERK/CREB signaling pathway in the hippocampus, promoting brain-derived neurotrophic factor (BDNF) synthesis (especially in females) to restore impaired long-term potentiation (LTP) in Alzheimers model mice

In addition, chronic treatment of rats with Sildenafil was found to restore the elevated biological markers of vasoconstrictors resulting from oxidative stress and cyclooxygenase to their normal levels [29]