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Targeting this pathway might also be a promising target to prevent POI in surgical patients ( s100 Protein in Glia Glial s100 protein is a marker of enteric glia but is also involved in inflammation caused by pathogenic bacteria such as infection with Clostridium difficile and it involved in UC and celiac diseases ( PPAR Receptors Targeting PPAR receptors with palmitoylethanolamide (PEA), a receptor agonist, can inhibit pro-inflammatory responses in reactive enteric glia in pre-clinical IBD models

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Although ascites is observed in other diseases, such as liver cirrhosis, it is most frequently observed with metastatic OVCA 1,4

conducted a randomized double-blind clinical trial to assess the preventive effect of curcumin, 70 patients with mild-to-moderate UC were randomly assigned to curcumin (1500 mg/day) or placebo intake for 8 weeks, and it was found taking curcumin supplements combined with medication treatment can significantly improve clinical outcomes and quality of life in patients with mild-to-moderate UC