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Indeed, the number of VOCs increased 1.2- to 1.8-fold (odorous VOCs: 2.0- to 3.7-fold), while the total amount increased 5.1- to 7.4-fold (7.7- to 13.6-fold) for bacteria grown in anaerobiosis when compared to those for bacteria grown in aerobiosis

Moving forward, emphasis should shift from reiterating preclinical challenges toward designing rigorous, biomarker-driven randomized controlled trials that can define their true clinical value

doi: 10.1038/s41583-019-0233-2 104 OrsiniFBlasioDDZangariRZanierERSimoniM-GD

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Curcumin increases the expression of Nrf2, HO-1, and GPX4 in hepatocytes, inhibits the decline of mitochondrial membrane potential in hepatocytes, and all these changes could be reversed by ferroptosis inducer erastin, indicating that curcumin protects against Wilsons disease by inhibiting ferroptosis