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Nature 424(6948):561565 Niki E, Yoshida Y, Saito Y, Noguchi N (2005) Lipid peroxidation: mechanisms, inhibition, and biological effects

For the sample-specific models per dataset, a drug essentiality score was calculated for each drug by determining the number of samples in which the drug reduced the biomass or the ATP production below the desired threshold for cancer and healthy models, respectively

Mean glucose disposal rates (M-values) were decreased by 36% in non-obese type 2 diabetic subjects and 58% in obese type 2 diahetic subjects compared to the control subjects

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The behavior of the individual components is described below