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These antioxidant systems convert ROS to nonharmful compounds and they also reduce disulfide bonds in oxidized proteins

Hsieh C-H, Shaltouki A, Gonzalez AE, da Cruz AB, Burbulla LF, Lawrence ES, et al

Research has demonstrated that augmented glutamine metabolism in CAFs gives rise to collagen-rich extracellular matrix and fosters tumor development [134, 135]

While the collapse of the immune privilege is considered as one of the most accepted theories accounting for AA, the exact pathogenesis of this disease remains unclear by now