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Less direct evidence comes from observations that mice with mutations of the POLG gene, which encodes a subunit of mtDNA polymerase, exhibit depression-like symptoms (Kasahara et al., 2006), and that polymorphisms of genes that code for mitochondrial enzymes, such as MTHFD1L, are associated with negative rumination, which is a precursor to depression (Moustafa et al., 2014)

In some edible mushrooms, such as Boletus edulis, mushrooms, and Phantom pilosula, the precursor histidine trimethyl lactone required for the synthesis of Ergothioneine can also be produced

found that TFPs significantly mitigated HFD-induced obesity in mice (41)

Marrs et al., 1995), petunia an9 (Anthocyanin 9

Therefore, the authors concluded that N-acetyl cysteine, alpha lipoic acid and bromelain combination showed promise to improve endometriosis-associated pelvic pain